LAight therapy

LAight therapy is a physical procedure for the outpatient treatment of acne inversa(hidradenitis suppurativa), acute abscesses and acne that has been approved since 2017 and was developed by the company LENICURA in Germany. In this combination therapy of different light spectra and radio frequency, affected areas are moistened with a contact gel and then irradiated with a special combination of different light waves and radio frequency. The medical device required for the treatment procedure has medical CE approval valid throughout Europe, but is only available in Germany and Austria.

There are several studies on hidradenitis suppurativa/acne inversa with this treatment regimen. For the endpoints of disease severity and treatment response, there are indications of an advantage of additional LAight therapy compared to topical drug therapy alone. With regard to the self-reported outcomes health-related quality of life, pain, depressive symptoms and anxiety symptoms, there was no evidence of an advantage or disadvantage for one of the treatment groups, taking clinical relevance into account. There were no indications of serious adverse events due to the use of LAight therapy. In the overall assessment across all endpoints, there is an indication of a benefit of additional LAight therapy compared to (topical) drug therapy alone in acne inversa with Hurley I and II severity. This is mainly due to significant and clinically relevant differences between the treatment groups in terms of disease severity and treatment response in one study (Strobel A et al. 2024).

Further studies are needed to confirm the benefit of this therapy in hidradenitis.

1. Strobel A et al. (2024) Real-world effectiveness and safety of the LAight-therapy in patients with hidradenitis suppurativa. J Dtsch Dermatol Ges 22:936-945.