Lactate

Lactate is the anion of lactic acid and the end product of anaerobic glycolysis and is transported to the liver via the Cori cycle. The determination of lactate is used for prognosis and follow-up control after intoxication and in metabolic acidosis.

Standard value: The standard value is between 9 and 16 mg/dl in serum and between 0.6 and 2.4 mmol/l in plasma

Pathologically increased: With acidosis: lactic acidosis, non-specific marker for tissue hypoxia: Shock, sepsis, CO poisoning, alcohol, methanol, salicat, acetaminophen poisoning, burns, advanced tumors, congenital metabolic disorders, infections such as HIV or malaria, acute kidney failure, cardiovascular failure, an excessive amount of anaerobic germs in the small intestine, biguan-induced lactic acidosis, ketoacidosis, thiamine deficiency,

Without acidosis: physical stress (competitive sports), post-operative, compensatory in hyperventilation, infusions, insulin therapy, administration of catecholaminergic substances.