KRT6C gene

Last updated on: 27.09.2024

Dieser Artikel auf Deutsch

Requires free registration (medical professionals only)

Please login to access all articles, images, and functions.

Our content is available exclusively to medical professionals. If you have already registered, please login. If you haven't, you can register for free (medical professionals only).


Requires free registration (medical professionals only)

Please complete your registration to access all articles and images.

To gain access, you must complete your registration. You either haven't confirmed your e-mail address or we still need proof that you are a member of the medical profession.

Finish your registration now

DefinitionThis section has been translated automatically.

KRT6C (Keratin 6C) is a protein-coding gene located on chromosome 12q13.13. An important paralog of this gene is KRT6B and KRTB9.

General informationThis section has been translated automatically.

Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. Type II keratins are clustered in a region of chromosome 12q13.

Diseases associated with KRT6C include:

  • epidermolytic palmoplantar keratosis (keratoderma) (EPPK)
  • Palmoplantar keratosis, non-epidermolytic, focal or diffuse
  • Pachyonychia congenita

LiteratureThis section has been translated automatically.

  1. Li P et al. (2023) Proteomic profiling reveals KRT6C as a probable hereterodimer partner for KRT9: New insights into re-classifying epidermolytic palmoplantar keratoderma (EPPK) and a milder form of pachyonychia congenita (PC-K6c) as a group of genetic cutaneous disorders. J Proteomics 287:104971.

Last updated on: 27.09.2024