Ki-67

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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DefinitionThis section has been translated automatically.

Histologically important marker for proliferating cells. Ki-67 (Ki = keel). The protein is detectable during the active G(1), S, G(2) and M phase of the cell cycle. Ki-67 is missing in the G(0) phase of resting cells. The protein is well suited as a marker to identify the proportion of proliferating cells in a population. Diagnostically significant is not only the density but also the distribution pattern of Ki-67 positive cells in the tissue.

LiteratureThis section has been translated automatically.

  1. Hantschke M et al (2016) Immunohistological techniques. In: L. Cerroni et al. histopathology of the skin. Springer Publishing House Berlin-Heidelberg p. 30.
  2. Ohsie SJ et al. (2008) Immunohistochemical characteristics of melanoma. J Cutan Pathol 35:433-444.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer