Iododerma tuberosum L27.1

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 03.08.2021

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Synonym(s)

Iododerm

Definition
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Drug exanthema caused by iodine-containing drugs. S.a. Bromoderm.

Localization
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Especially in the facial area; in the area of the nose. The legs can also be affected.

Clinical features
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Nodular, reddish-brown, inflammatory changes of the skin with ulcer-crusted surface and pustular rim.

Histology
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Granulomatous inflammation in the corium, pseudocarcinomatous epidermal hyperplasia, intraepidermal abscess formation.

Diagnosis
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Increased iodine excretion in the urine.

External therapy
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Antiphlogistic ointments such as 5% dexpanthenol cream. S.a.u. Bromoderm.

Internal therapy
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Stop the iodine therapy. Immediate measures with 5-10% sodium thiosulfate solution and 0.9% sodium chloride solution i.v. as well as table salt p.o. if necessary. Application of systemic glucocorticoids such as prednisolone (e.g. Decortin H) initially 40-80 mg/day i.v., slowly balance out.

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Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 03.08.2021