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Intermediate leprosyA30.8

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

borderline leprosy; Dimorphic leprosy; Leprosy Borderline leprosy

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DefinitionThis section has been translated automatically.

Boderline form of leprosy standing between multibacillary leprosy lepromatosa and paucibacillary leprosy tuberculoides Untreated, this unstable form of leprosy turns into leprosy lepromatosa.

ClassificationThis section has been translated automatically.

There are 3 clinical forms:

  • borderline tuberculoid leprosy (BT)
  • Mid Borderline Leprosy (BB)
  • Borderline leprosy (BL)

Clinical featuresThis section has been translated automatically.

Symmetrically (trunk) or asymmetrically (face) localized, isolated or confluent, succulent, scaly plaques, possibly bordered anular with nodular bulges. Initially general disease symptoms with muscle weakness. More rarely, alopecia foci or asymmetrical polyneuritis occur.

LaboratoryThis section has been translated automatically.

The lepromin reaction is positive or negative, depending on the immunity situation.

HistologyThis section has been translated automatically.

Tuberculoids and lepromatous structures depending on leprosy tuberculoides or leprosy lepromatosa, pathogen detection possible

DiagnosisThis section has been translated automatically.

Type of skin symptoms, sensitivity test with needle and cotton swab. Bact. Swab (Ziehl-Neelsen stain) from the nasal mucosa. Possible thickening of the cervical nerves.

TherapyThis section has been translated automatically.

According to the leprosy.

Progression/forecastThis section has been translated automatically.

This "intermediate" form of leprosy can develop into paucibacillary tuberculoid leprosy (usually with sufficient therapy) as well as into multibacillary lepromatous leprosy (in case of insufficient or no therapy).

LiteratureThis section has been translated automatically.

  1. Arif T et al (2019) Leprosy in the post-elimination era: a clinico-epidemiological study from
    anorthern Indian tertiary care hospital. Acta Dermatovenerol Alp Pannonica Adriat 28:7-10.
  2. Bhat RM et al (2003) A case report of fatal dapsone-induced agranulocytosis in an Indian mid-borderline leprosy patient. Lepr Rev 74: 167-170
  3. Daniel E et al (2003) Ocular complications in incident relapsed borderline lepromatous and lepromatous leprosy patients in south India. Indian J Ophthalmol 51: 155-159
  4. Fucha J et al (1992) Diagnostic and therapeutic problems in leprosy patients from a dermatological point of view. Act Dermatol 18: 231-235
  5. Lawn SD et al (2003) Borderline tuberculoid leprosy: an immune reconstitution phenomenon in a human immunodeficiency virus-infected person. Clin Infect Dis 36: e5-6
  6. Zorbas P et al (1999) Borderline tuberculoid leprosy coexisting with systemic lupus erythematosus. J Eur Acad Dermatol Venereol 12: 274-275

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer