Interferon alpha-2b

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

IFN α-2b; IFN-α-2b; INF alpha-2b; interferon alpha-2b; interferon-alpha-2b; Interferon-α-2b

Definition
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Half-life
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2–3 h

Indication
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Hair cell leukemia, HIV-associated Kaposi sarcoma, remission maintenance in centroblastic-centrocytic non-Hodgkin lymphomas, melanoma, malignant.

Limited indication
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Pregnancy, lactation, psoriasis, COLD, diabetes mellitus tending to ketoacidosis, coagulation disorders, patients < 18 years.

Dosage and method of use
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2-5 million IU/m2 KO s.c., for Kaposi sarcoma 5 million IU/m2 KO 3 times/week.

Notice! Women of childbearing age should use effective contraception under therapy.

Undesirable effects
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S. Interferon alfa-2a.

Notice! In case of hypersensitivity reactions ( urticaria, angioedema, bronchospasm) the drug should be discontinued immediately!

Interactions
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Enhanced effect of xanthine derivatives, s.a. Interferon alfa-2a.

Contraindication
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Autoimmune diseases, psychiatric history, immunosuppressive treatment.

Preparations
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intron A

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Last updated on: 29.10.2020