Indomethacin
DefinitionThis section has been translated automatically.
Antirheumatic with weak analgesic and antipyretic effects. S.a.o. anti-inflammatory, non-steroidal.
IndicationThis section has been translated automatically.
Chronic polyarthritis (rheumatoid arthritis), juvenile chronic arthritis, arthrosis, Bechterew's disease, acute infections of the locomotor system, gout attack, lumbalgia. sprains, strains. Post-operative pain, inflammation, swelling, dysmenorrhea.
Dosage and method of useThis section has been translated automatically.
- Adults: 2-3 times/day 25-50 mg p.o., if necessary slow dose increase. Recommended maximum dose: 200 mg indomethacin/day. The capsules or suspension should always be taken with meals.
- Dose for children: Children from 2 years of age initial, divided into 2-3 doses, 1-3 mg/kg bw/day. This dose may be increased weekly to a maximum daily dose of 4 mg/kg bw or up to 150 to 200 mg/day, whichever is the lower daily dose of both. After improvement of symptoms reduction to the lowest possible maintenance dose.
Undesirable effectsThis section has been translated automatically.
Very frequent or frequent gastrointestinal complaints such as gastritis, flatulence, dyspepsia as well as headaches, drowsiness, drowsiness, exhaustion. Rare exanthema, angioneurotic edema, petechiae or ecchymoses, purpura, alopecia, elevated transaminases.
InteractionsThis section has been translated automatically.
Increased toxicity of ciclosporin, antihypertensive crises under phenylpropanolamine, increased plasma levels of indometacin with probenecid, delayed elimination of penicillin. Furosemide accelerates the excretion of indomethacin.
ContraindicationThis section has been translated automatically.
Analgesic NSAID intolerance(e.g. bronchial asthma, skin reactions). Children under 2 years of age. Inducible porphyria.
PreparationsThis section has been translated automatically.
Amuno, Indomet-ratiopharm
Note(s)This section has been translated automatically.
Responsiveness in road traffic may be impaired.