Immunoglobulins, specific

Synonym(s)

Hyperimmunoglobulin; Pseudomonas immunoglobulin; Rubella immunoglobulin; TBE immunoglobulin

Immunoglobulins, which contain antibodies against certain diseases in particularly high concentrations. See tab.

Immunoglobulin	Indication	Dosage	Finished preparation
hepatitis B	Hepatitis B prophylaxis in case of increased risk of infection (dialysis, needlestick injuries)	Simultaneous prophylaxis (simultaneously with the 1st dose of HBV vaccine): 0.06 ml/kg bw i.m. For newborns: total dose of 1 ml i.m.	Hepatitis B immunoglobulin Behring
		In case of exposure/suspicion (no simultaneous prophylaxis with HBV vaccine): at least 0.06 ml/kg bw i.m., repeat with same dose after 4 weeks.
		In case of massive exposure (e.g. after transfusion of HBV-infected blood or blood components): at least 0.12 ml/kg bw i.m.
		Continuous prophylaxis 0.06 ml/kg bw at intervals of 3 months

CMV	Prophylaxis of CMV infections after transplantation or in HIV patients with < 50 CD4 cells/μl	50-100 IU/kg bw i.v. every 14 days, according to clinical course	Cytotect

VZV	Prophylaxis of varicella in immunocompromised patients,	1 ml/kg bw i.v. within 3 days after exposure	e.g. Varitect
	Herpes zoster in immunocompromised patients	2 ml/kg bw i.v.