Imipramine

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Thymoleptic, antidepressant.

Indication
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Depressive syndromes regardless of their nosological classification, also long-term pain treatment.

Undesirable effects
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Dermatologically significant: exanthema, photosensitivity, edema, hair loss, hyperhidrosis. Occasional increase of anxiety and agitation, turning into hypomania or mania, paresthesia, headache, in individual cases activation of psychotic symptoms, aggressiveness.

After at least 2 years of therapy, dyschromasia may occur in the exposed skin areas (complexation of imipramine with melanin). Successful treatments with the Q-switched alexandrite laser or the ruby laser have been described.

Remember! Active participation in road traffic is impaired.

Contraindication
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Heart attack, do not administer ampoules together with diclofenac sodium inj. solution. Cave! Severe kidney disease or adrenal market tumor.

Preparations
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Tofranil

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Dyschromia;

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Last updated on: 29.10.2020