Hypromellose-adhesive paste 40% (nrf 7.8.)

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Formulation
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Rp.

Hypromellose 2000 40,0
Hydrophobic base gel DAC ad 100,0

As a protective agent for mucosa and skin, also as an adhesive paste base for the incorporation of additional drugs (e.g. corticosteroids tretinoin, zinc oxide).

The hydrophobic matrix contains the water-soluble swelling agent Hypromellose 2000 a cellulose derivative. The hypromellulose is embedded as solid particles in the hydrophobic base and swells on contact with the moist mucosa. This leads to a strong adhesion to the mucosa. The solubility of the water-free base is low. Pharmaceuticals can be incorporated in very finely powdered form or microfine.

Usage period: tube: 3 years; dispenser box: 3 months

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Last updated on: 29.10.2020