Hypertriglyceridemia familialE78.1
Synonym(s)
carbohydrate-induced hyperlipidemia; carbohydrate-induced triglyceridemia; Endogenous hyperlipemia; Endogenous hypertriglyceridemia; Familial hypertriglyceridemia; Hyperlipemia endogenous; Hyperlipidemia carbohydrate-induced; Hyperlipoproteinemia type IV; Hyperprebetalipoproteinemia; Hypertriglyceridemia endogenous; Triglyceridemia carbohydrate-induced
DefinitionThis section has been translated automatically.
Molecular genetic inconsistent hyperlipoproteinemia often characterized by a decrease of HDL and an increase of triglycerides.
Occurrence/EpidemiologyThis section has been translated automatically.
Prevalence is 1-2/100
LocalizationThis section has been translated automatically.
Mainly buttocks, thigh flexion sides.
Clinical featuresThis section has been translated automatically.
Clinically, the lipid metabolism disorder manifests itself as "hyperlipoproteinemia type 4" according to Fredrickson with obesity, peripheral circulatory disorders (arteriosclerosis), coronary insufficiency, multiple xanthomatosis, papular, normolipemic, even striated xanthomas along the hand lines. There is also an increased risk of pancreatitis. Possibly fatty liver and diabetes type 2.
LaboratoryThis section has been translated automatically.
Serum is clear or milky turbid; increase of pre-β lipoproteins, triglycerides and reduced glucose tolerance.
TherapyThis section has been translated automatically.
Metabolic adjustment in cooperation with the internist; possibly surgical removal of the xanthomas.