Hyperhidrosis, drug-inducedR61.9
DefinitionThis section has been translated automatically.
Drug-induced hyperhidrosis is a secondary, generalized hyperhidrosis. In this case, individual body regions can sweat more.
EtiopathogenesisThis section has been translated automatically.
The following list of possible causative substances is a selection and does not claim to be complete and is subject to the constantly changing pharmaceutical market.
- ACE inhibitors:
- Enalapril
- Quinapril
- Telmisartan.
- Acetylsalicylic acid
- Acetycholinesterase inhibitors:
- Neostigmine
- Physostigmine.
- alpha-receptor blocker:
- Doxazosin
- Terazosin.
- Antiallergics:
- Antiarrhythmics:
- Adenosine.
- antibiotics:
- Antidepressants:
- Citalopram
- Fluvoxamine
- Fluoxetine
- Doxepin
- Imipramine.
- Antiestrogens:
- Tamoxifen
- Toremifs.
- Anticonvulsants:
- Topiramate.
- Antiparasitic drugs:
- Lindane (no longer registered in Germany since 2008).
- Asthma drugs:
- Stimulant/Appetite suppressant:
- Amphetamines
- Cocaine
- Ephedrine
- Pseudoephedrine.
- Beta-receptor blockers (usually reduction of hyperhidrosis; exception):
- carvedilol.
- Calcium antagonists:
- nifedipine
- Isradipin
- Nimodipine.
- Calcium-containing compounds (oral and i.v.)
- cholinergics:
- Neostigmine
- Pyridostigmine
- Distigmine.
- Fibrinolytics
- Luxury poisons/drugs:
- alcohol
- Nicotine
- Caffeine.
- Glaucoma Therapeutics
- Vaccines
- Insulin
- Interferons (see below interferon alfa-2a)
- Iodine-containing X-ray contrast medium.
- Migraine agents:
- Muscle relaxants:
- neuroleptics:
- Clozapine
- Sulpiride.
- Opioids:
- Morphine
- Heroin
- Buprenorphine
- Tramadol
- Tilidin
- Paracetamol.
- Parasympathomimetics:
- Acetylcholine
- Pilocarpine
- Muscarin.
- Parkinson drugs (dopaminergic preparations)
- Prostaglandins
- Pyrazolones:
- Retinoids (dose-dependent):
- Sympathomimetics (systemic):
- ephedrine
- Pseudoephedrine
- Pholerin
- Methyphenidate
- Phenylephrine
- Dopamine
- Etilefrin
- Norfenefrin
- Oxilofrin
- Amfepramon
- Pemolin.
- Sympathomimetics (applied locally, e.g. eye and nose, less frequently leading to hyperhidrosis than systemic sympathomimetics):
- Virustatics:
- vitamins:
- VitaminB1 (thiamine and derivatives).
- Contraction inhibitor:
Clinical featuresThis section has been translated automatically.
S.u. Hyperhidrosis.
TherapyThis section has been translated automatically.
If possible, the medication that triggered the reaction should be discontinued. If therapy is desired or if discontinuation is not possible, local therapy or supportive systemic therapy should be used. See below hyperhidrosis.