Synonym(s)
HRGP
DefinitionThis section has been translated automatically.
HRGP is an antagonist of fibrinolysis, which is produced in the thrombocytes (see below fibrinolysis antagonists). It binds to fibrin and fibrinogen. HRGP is a competitive inhibitor of plasminogen due to its high binding capacity to the lysine binding sites. This inhibits fibrinolysis. 50% of the plasminogen and alpha-2-antiplasmin are bound to the HRGP.
LiteratureThis section has been translated automatically.
- HA Neumann (2014) The coagulation system. ABW-Wissenschaftsverlag GmbH Berlin p. 113.
Prof. Dr. med. Peter Altmeyer