Guidelines, evidence-based

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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  • Instrument for the implementation of evidence-based medicine with the help of recognized evidence, based on the best scientific, objectifiable and verifiable evidence available today (see below study, clinical). An evidence-based guideline should enable a physician to practice medicine of the highest possible standard according to the current state of knowledge. The development stages of guidelines (S1-S3) differ, according to the methods of the AWMF, in the extent of the systematic literature search and the structuring of the consensus process.
    • S1-Guideline: The recommendation prepared by a representative group of experts of the scientific medical society in informal consensus, which is adopted by the board of the society.
    • S2-Guideline: Can be developed from formally evaluated statements of the scientific literature and can be discussed and adopted in a formalized consensus process.
    • S3-Guideline: All elements of a systematic guideline development are applied.
  • The evidence-based strategy of guideline development is characterized by:
    • Systematic search, evaluation and synthesis of the best available scientific evidence
    • Derivation of the procedure recommended in the guideline from scientific evidence
    • Exact documentation of the connection between the respective recommendation and the associated evidence level
    • Selection of the evidence-based key recommendations of a guideline using formalised consensus procedures.

Literature
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  1. Boehncke WH et al (2007) Literature review with instruments of evidence-based medicine: an introduction based on a dermatological therapy study. JDDG 9: 793-800
  2. Guidance Manual of AWMF and ÄZQ

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Last updated on: 29.10.2020