Synonym(s)
Granuloma anulare multiforme; Granuloma multiforme; Mkar disease; Mkar Disease; Nkanu disease
HistoryThis section has been translated automatically.
Leiker, 1964
DefinitionThis section has been translated automatically.
A chronic, granulomatous skin disease of unknown etiology, frequently occurring in Central Africa. Possibly identical with actinic granuloma.
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Occurrence/EpidemiologyThis section has been translated automatically.
Especially in Central and East Africa.
ManifestationThis section has been translated automatically.
Mostly adults, gynecotropia.
LocalizationThis section has been translated automatically.
Mainly arms and hands, upper torso, head.
Clinical featuresThis section has been translated automatically.
HistologyThis section has been translated automatically.
Circumscribed necrobiosis foci in the corium with peripheral histiocytic border wall and numerous giant cells.
Differential diagnosisThis section has been translated automatically.
TherapyThis section has been translated automatically.
No useful therapy modalities are known.
Progression/forecastThis section has been translated automatically.
Eminently chronic disease with a course lasting months to years. Spontaneous healing after years is described.
LiteratureThis section has been translated automatically.
- Garrett AS (1999) Granuloma multiforme (called Nkanu disease in the 1940s and Mkar disease in 1964) Int J Lepr Other Mycobact Dis 67: 172-174
- Krampitz HE (1967) Granuloma multiforme Leiker. dermatologist 18: 365-368
- Leiker DL et al (1964) Granuloma multiforme. A new disease resembling leprosy. Int J Lepr 32: 368-370.
- Rogge T (1977) Granuloma multiforme. Dermatologist 28: 375-377
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Outgoing links (8)
Granuloma actinic; Granuloma anulare classic type; Granulomatosis disciformis chronica et progressiva; Leprosy (overview); Papel; Pruritus; Sarcoidosis of the skin; Tuberculosis cutis luposa;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer