Foot-and-mouth disease, realB08.8
Synonym(s)
Aphthenic Disease; aphthosis epizootica; aphthous fever; foot and mouth disease; stomatitis epidemica
HistoryThis section has been translated automatically.
Frog and Spoonbill, 1897
DefinitionThis section has been translated automatically.
Viral zoonosis transmitted to humans from cloven-hoofed animals (cattle, pigs, sheep) through direct contact, rarely through infected objects or dairy products.
PathogenThis section has been translated automatically.
Foot-and-mouth disease virus (FMD virus belonging to the family of picornaviruses -Picornaviridae)
LocalizationThis section has been translated automatically.
Entry portal: Mainly skin and mucous membranes of the upper respiratory and digestive tract.
Clinical featuresThis section has been translated automatically.
- Incubation period: 2-6 days.
- Prodromal stage with fever, headache, fatigue and back pain.
- After 2-3 days: bladder at the entrance of the pathogen.
- Viraemic phase: Reddened oral mucosa, morbilliform exanthema. Aphthous lesions, up to the size of a lens, on the mucous membranes of the mouth, throat, tongue and lips as well as on the soles of the feet, palms of the hands and fingertips.
HistologyThis section has been translated automatically.
Intraepidermal bladder, eosinophilic cell pycnosis, reticular degeneration.
DiagnosisThis section has been translated automatically.
Virus isolation (tissue cultures), complement fixation reaction.
Differential diagnosisThis section has been translated automatically.
Complication(s)This section has been translated automatically.
Bacterial secondary infections, gastroenteritis, orchitis, nephritis, myocardial damage.
TherapyThis section has been translated automatically.
Symptomatic, e.g. 1% Clioquinol lotion or cream (e.g. R050, Linola-Sept).
Cave!
Notification of the responsible veterinarian! No obligation to notify sick people.Progression/forecastThis section has been translated automatically.
Inexpensive, scarless healing within 14 days.
LiteratureThis section has been translated automatically.
- Loeffler F, Frosch P (1897) Summary report on the results of the investigations carried out by the Commission for Research on Foot and Mouth Disease at the Institute for Infectious Diseases. German Med Vschr 98: 80-84