Foot-and-mouth disease, real B08.8

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Aphthenic Disease; aphthosis epizootica; aphthous fever; foot and mouth disease; stomatitis epidemica

History
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Frog and Spoonbill, 1897

Definition
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Viral zoonosis transmitted to humans from cloven-hoofed animals (cattle, pigs, sheep) through direct contact, rarely through infected objects or dairy products.

Pathogen
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Foot-and-mouth disease virus (FMD virus belonging to the family of picornaviruses -Picornaviridae)

Localization
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Entry portal: Mainly skin and mucous membranes of the upper respiratory and digestive tract.

Clinical features
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  • Incubation period: 2-6 days.
  • Prodromal stage with fever, headache, fatigue and back pain.
  • After 2-3 days: bladder at the entrance of the pathogen.
  • Viraemic phase: Reddened oral mucosa, morbilliform exanthema. Aphthous lesions, up to the size of a lens, on the mucous membranes of the mouth, throat, tongue and lips as well as on the soles of the feet, palms of the hands and fingertips.

Histology
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Intraepidermal bladder, eosinophilic cell pycnosis, reticular degeneration.

Diagnosis
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Virus isolation (tissue cultures), complement fixation reaction.

Differential diagnosis
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Complication(s)
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Bacterial secondary infections, gastroenteritis, orchitis, nephritis, myocardial damage.

Therapy
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Symptomatic, e.g. 1% Clioquinol lotion or cream (e.g. R050, Linola-Sept).

Cave!

Notification of the responsible veterinarian! No obligation to notify sick people.

Progression/forecast
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Inexpensive, scarless healing within 14 days.

Literature
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  1. Loeffler F, Frosch P (1897) Summary report on the results of the investigations carried out by the Commission for Research on Foot and Mouth Disease at the Institute for Infectious Diseases. German Med Vschr 98: 80-84

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020