Fibromatosis digital infantile M72.8

Rare, benign, myofibroblastically differentiated tumour on fingers or toes in infants and small children, with a tendency to infiltrative growth. Very rare in adults.

Congenital (approx. 30% of cases), occurring shortly after birth or in the first months of life, or more rarely acquired later.

Dorsal or lateral side of fingers or toes (except thumbs and big toes)

Fuzzily defined, moderately cell-rich tumor parenchyma arranged in vertebrae and fascicles, whose spindle cells are partially oriented perpendicular to the epidermis. The tumor cells have a poorly delimited, moderately eosinophilic cytoplasm with eosinophilic inclusion bodies. They react positively with desmin and alpha-smooth muscular actin.

1. Hügel et al (1995) Fibromatoses and other fibroblastically/myofibroblastically differentiated connective tissue tumors from the dermatologist's point of view. Z Hautkr 70: 717-724
2. Kanwar AJ et al (2002) Congenital infantile digital fibromatosis. Pediatric Dermatol 19: 370-371
3. Kawaguchi M et al (1998) A case of infantile digital fibromatosis with spontaneous regression. J Dermatol 25: 523-526
4. Reye RDK (1965) Recurring digital fibrous tumor of childhood. Arch pathogen 80: 228-231
5. Sarma DP, Hoffmann EO (1980) Infantile digital fibroma-like tumour in an adult. Arch Dermatol 116: 578-579