Fat embolismT79.1
DefinitionThis section has been translated automatically.
Embolisation of the terminal vessels, especially of the lungs, but also of the skin, kidneys and brain by fat particles. Clinically characterized by the triad petechiae, dyspnoea, cerebral symptoms.
EtiopathogenesisThis section has been translated automatically.
- After trauma: comminuted fractures of the long tubular bones (release of yellow bone marrow), extensive soft tissue injuries and contusions, and after burns.
- Without previous trauma: necrotizing pancreatitis, intoxication, consumption coagulopathy, shock, eclampsia, viral hepatitis, SLE.
- Iatrogen: parenteral nutrition, propofol infusion, chemotherapy, granulocyte colony stimulating factor therapy ( Filgrastim, Lenograstim).
Clinical featuresThis section has been translated automatically.
- Integument: Petechial haemorrhages, preferably on the neck, back, shoulders, axillae, conjunctiva. Usually 2-3 days after trauma, possibly occurring later.
- Extracutaneous manifestations: signs of respiratory insufficiency: dyspnoea, cyanosis, tachycardia. Cerebral dysfunction: agitation, irritability, hallucinations, somnolence.
TherapyThis section has been translated automatically.
Internal medicine: Stabilization of circulation, oxygenation. Specific therapy not known.