Famciclovir
DefinitionThis section has been translated automatically.
Virustatic.
Half-lifeThis section has been translated automatically.
2 h
Pharmacodynamics (Effect)This section has been translated automatically.
Nucleoside analogue, easily absorbable precursor of penciclovir. Is converted into penciclovir in the organism.
IndicationThis section has been translated automatically.
Herpes zoster virus, also effective for herpes simplex infections.
Limited indicationThis section has been translated automatically.
Herpes zoster generalisatus, herpes zoster ophthalmicus, zoster encephalitis (lack of clinical experience).
Pregnancy/nursing periodThis section has been translated automatically.
Contraindicated.
Dosage and method of useThis section has been translated automatically.
- 3 times/day 250 mg p.o. over 7 days.
- Dose reduction depending on creatinine clearance: 30-59 ml/min. 2 times/day 250 mg p.o.; < 30 ml/min: once/day 250 mg p.o.
Undesirable effectsThis section has been translated automatically.
Headache, abdominal pain, nausea, creatinine surge.
InteractionsThis section has been translated automatically.
s. Table 1.
ContraindicationThis section has been translated automatically.
Pat. < 18 years, immunocompromised patients < 25 years (insufficient data!), Pat > 50 years. (limited experience, insufficient data).
PreparationsThis section has been translated automatically.
Famvir, Famvir Zoster
Note(s)This section has been translated automatically.
Remember! The tablets should be taken with sufficient liquid!
TablesThis section has been translated automatically.
Main interactions of Famciclovir
Anti-inflammatories, non-steroidal |
Famciclovir mirror ↑ |
Cimetidine |
Famciclovir mirror ↑ |
Digoxin |
Digoxin level ↑ |
Furosemide |
Famciclovir mirror ↑ |
Penicillin |
Famciclovir mirror ↑ |
Probenecid |
Famciclovir mirror ↑ |
Theophylline |
Famciclovir mirror ↑ |
Thiazide diuretics |
Famciclovir mirror ↑ |