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Erythema papulatum centrifugumL53.1

Last updated on: 18.12.2023

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HistoryThis section has been translated automatically.

Watanabe, 1962

DefinitionThis section has been translated automatically.

Rare figured, often anular, recurrent exanthema described mainly in the Japanese literature (to date just over 150 cases have been described).

Occurrence/EpidemiologyThis section has been translated automatically.

Adulthood; m>w

EtiopathogenesisThis section has been translated automatically.

Viral infections e.g. by parvoviruses? (Nakagawa H et al. 2020).

LocalizationThis section has been translated automatically.

V.a. Extermities

Clinical featuresThis section has been translated automatically.

Erythema papulatum centrifugum (EPC) differs from other well-described figural exanthemas. It is characterized by a:

  • Recurrent, expanding exanthema with anular or circular red plaques surrounded by punctate (eccrine associated) red papules.

The lesions occur periodically in episodes and (apparently) resolve completely in the interim.

Patients have no other associated cutaneous or internal diseases.

HistologyThis section has been translated automatically.

The histopathologic feature shows superficial perivascular inflammation paracecrine infiltrates.

Differential diagnosisThis section has been translated automatically.

Erythema anulare centrifugum

LiteratureThis section has been translated automatically.

  1. Franco A et al (2018) A pruritic annular eruption: answer. Am J Dermatopathol 40: 386.
  2. Nakagawa H et al. (2020) Parvovirus Infection Diagnosed Using the Patient's smartphone photographs. Intern Med 59: 3257-3258.
  3. Ohmori R et al. (2013) A new type of annular erythema with perieccrine inflammation: erythema papulatum centrifugum. Dermatology 226: 298- 301.
  4. Rodríguez-Lomba E et al.(2018) An atypical figurate erythema with seasonal recurrences. JAMA Dermatol154: 1340- 1341.
  5. Song Z et al. (2012) Erythema papulosa semicircularis recidivans: a new reactive dermatitis? Dermatitis 23: 44- 47.
  6. Valencia-Herrera A et al. (2023) Asymmetrical Periflexural Exanthema Associated with SARS-CoV-2 Infection in a Paediatric Patient. Acta Derm Venereol 103:adv00839.
  7. Zhang LW et al. (2020) Erythema papulatum centrifugum and new diagnostic criteria. Australas J Dermatol 61:e87-e90.

Last updated on: 18.12.2023