Epidermophyton floccosum

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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History
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Langeron and Milochevitch, 1930

General definition
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Anthropophilic dermatophyte. Transmission through contaminated laundry, skin contact and intimate intercourse.

Occurrence/Epidemiology
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Worldwide spread. Share of dermatophytes in Central Europe approx. 3-5%. Men are affected to 80-90%.

Manifestation
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Predilection sites: inguinal area, toe area with or without nail infestation.

Clinical picture
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Infection restricted to the stratum corneum. Invasive growth only if immune function is impaired. S.u. tinea; especially tinea corporis, tinea manuum, tinea pedum, tinea inguinalis. Nail and hair follicle infestation possible; never hair infestation. After infection of the interdigital spaces between the toes, picture of Tinea intertriginosa.

Microscopy
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  • Septed, hyaline, strongly branched hyphae with bulb-like ends.
  • Chlamydospores: Often terminal and intercalated, size: 10-20 μm Ø.
  • No microconidia.
  • Macroconidia: Numerous, club- or flail-shaped, smooth-walled, thin-walled, lateral or terminal on the hyphae, solitary or grouped, 2-10 chambers (size: 10-40 μm).

Literature
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  1. Degreef JH et al (1994) Current therapy of dermatophytosis. J Am Acad Dermatol. 31: S25-S30
  2. de Hoog GS et al (2000) Atlas of Clinical Fungi, 2nd ed, vol. 1 Centraalbureau voor Schimmelcultures (Utrecht, The Netherlands)
  3. Langeron M, Milochevitch S (1930) Morphology of the dermatophyte. Ann Parasitol hum comp 8: 465-508
  4. Seddon ME et al (1997) Invasive disease due to Epidermophyton floccosum in an immunocompromised patient with Behçet's syndrome. Clin Infect Dis 25: 153-154

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Last updated on: 29.10.2020