DefinitionThis section has been translated automatically.
Stevens-Johnson syndrome/toxicepidermal necrolysis (SJS/TEN) are rare, primarily drug-induced, acutely life-threatening diseases of the skin and mucous membranes. Both are considered variants of one disease entity, epidermal necrolysis, with varying degrees of severity.
ClassificationThis section has been translated automatically.
Depending on the extent of the epidermolytic skin changes, toxic epidermal necrolysis is divided into:
- Stevens-Johnson syndrome - defined as an epidermal detachment < 10% in relation to the body surface area (KOF)
- Toxic epidermal necrolysis (TEN ) - defined as an epidermal detachment of > 30 % KOF
- SJS/TEN transitional form - defined as an epidermal detachment between 10 and 30% KOF
