Eosinophilic panniculitis M79.3

Eosinophilic panniculitis is not a distinct entity but a polyetiological (eosinophilic) form of reaction of the subcutaneous adipose tissue to different systemic or external noxious agents such as:

• Drugs (Batalla A et al. 2013)
• parasites (Recuero JK e al. 2019; Perez C et al. 2000)
• Viruses (COVID-19) (Leis-Dosil VM et al. 2020).
• Various foreign materials.

Furthermore, a wide spectrum of associated inflammatory (Shiraishi K et al 2018) and neoplastic diseases (including T-cell lymphomas) have been described to be associated with hematoeosinophilia. In the context of the COVID 19 pandemic, one case of eosinophilic panniculitis has been reported (Leis-Dosil VM et al. 2020).

Histologically both eosinophilic lobar and eosinophilic septal panniculitis can be detected.

1. Batalla A et al. (2013) Eosinophilic panniculitis after subcutaneous administration of sodium heparin. Indian J Dermatol Venereol Leprol 79:849.
2. Flores-Terry MA et al (2018) Eosinophilic panniculitis associated with low complement and a paraproteinaemia. Semergen 44:e68-e70.
3. Jain S et al (2015) Eosinophilic panniculitis in a female child: An unusual presentation. Indian Dermatol Online J 6:34-36.

4. Leis-Dosil VM et al (2020) Eosinophilic panniculitis Associated With COVID-19. actas dermosifiliogr111:804-805.

5. Perez C et al (2000) Recurrent eosinophilic panniculitis associated with Fasciola hepatica infection. J Am Acad Dermatol 42(5 Pt 2):900-902.

6. Recuero JK e al. (2019) Eosinophilic panniculitis associated with toxocariasis in a child. An Bras Dermatol 94:250-251.

7. Shiraishi K et al (2018) Wells' syndrome associated with eosinophilic panniculitis presenting with multiple subcutaneous nodules. Eur J Dermatol 28:700-701.