Endometriosis cutaneous N80.6

Rokitansky 1860

Very rare, benign growth of endometric glandular tissue and stroma in the skin.

Very rare occurrence.

The estimated incidence of umbilical endometriosis is 0.5-1.0% of all extragenital endometrial ectopias (Note: about 10-15% of women of reproductive age suffer from endometriosis). In a larger study (n=33 women) the mean age of onset of cutaneous endometriosis was 35.4 ± 2.33 years (Lopez-Soto A et al. 2018).

About 70% of all cutaneous endometrioses develop secondarily in surgical scars. The most widespread assumption is therefore that the disease is preceded by the iatrogenic implantation of endometric cells through surgical procedures. In the case of spontaneous cutaneous endometriosis, the carry-over of endometrial particles via the blood or lymph channels is postulated.

Sexually mature women, especially after the age of 35. The average age in larger studies was 34.6 years.

Mainly umbilical, inguinal and genital regions, often in surgical scars of the caesarean section.

Mostly over several years slowly growing, surface-smooth, 0.5-3.0 cm large, soft to bulging elastic nodes of lighter to darker blue or red colouring; often cyclical premenstrual feeling of tension or also (distinct) pain (in about 50% of patients). Recurrent inflammation and bleeding may also occur.

The bioptate shows glandular and stroma tissue of the uterine mucosa

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2. Costa IM et al (2014) Cutaneous endometriosis: dermoscopic findings related to phases of the female hormonal cycle. Int J Dermatol 53:e130-132
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4. Fernández Vozmediano JM et al (2010) Cutaneous endometriosis. Int J Dermatol 49: 1410-1412
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