Elvitegravir

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Antiretrovirally active substance for the treatment of HIV infection. Inhibitor of the HIV integrase ( strand transfer inhibitor). Chemically, it is a compound reminiscent of quinolone antibiotics, but has no antibacterial activity and no quinolone-associated side effects.

Dosage and method of use
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According to ongoing phase III studies: 1-2 times/day 50-125 mg each in combination with 100 mg ritonavir and/or an active protease inhibitor.

Undesirable effects
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Rarely nausea, dizziness, headaches, diarrhoea and fever. Due to the study situation no long-term data are available.

Note(s)
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Remember! Currently (as of 6/2009) Elvitegravir is only available via an Expanded Access Program for patients with viral resistance to at least one drug of the substance classes NRTI, NNRTI and PI!

Incoming links (1)

Integrase inhibitors;

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Last updated on: 29.10.2020