Eccrine angiomatous hamartoma Q85.8

Hyman et al. 1968

Rare, benign malformation (hamartoma) of eccrine glands and thin-walled vascular proliferates.

m:f=6:4

Congenital or in early childhood. Occasionally also in old age.

Lower excrement (61%); here on the soles of the feet, more rarely on the field skin of the lower leg. Less frequently the palms of the hands are affected. Occasionally, other localizations have also been found (head and neck region, trunk).

Slowly growing or constant, mostly painful, predominantly solitary (disseminated or systematized multiple hamartomas are rarer), gray-blue, blue-red or red-brown, firm to very rough plaque or corresponding nodules with a smooth or verrucous surface. Combinations with hypertrichosis and focal hyperhidrosis, as well as a depigmentosus and spilus n evus have been described (Yamamoto T et al. 2017). S.a.under Hamartoma, eccrines.

In the middle dermis lobularly grouped sweat glands and glandular ducts with eccrine and apocrine differentiation in close mixture with capillary and cavernous dilated vessels. Hyperplastic epidermis. If the hamartoma is found outside the inguinal skin, immature hair follicles may still be involved in this complex nevus.

1. Laeng RH et al. (2001) Late-onset eccrine angiomatous hamartoma: clinical, histological and immaging findings. Dermatology 203: 70-74
2. Martinelli PT et al. (2003) Eccrine angiomatous hamartoma: a case report and review of the literature. Cutis 71: 449-455
3. Nakatsui TC et al. (1999) Eccrine angiomatous hamartoma: report of a case and literature review. J Am Acad Dermatol 41: 109-111
4. Patterson AT et al. (2016) Eccrine Angiomatous Hamartoma: A Clinicopathologic Review of 18 Cases. Am J Dermatopathol PubMed PMID: 26760684.
5. Pelle MT et al (2002) Eccrine angiomatous hamartoma. J Am Acad Dermatol 47: 429-435
6. Sanusi T et al. (2015) Eccrine Angiomatous Hamartoma: A Clinicopathological Study of 26 Cases. Dermatology 231:63-69.
7. Shin J et al. (2013) Eccrine angiomatous hamartoma: a review of ten cases. Ann Dermatol 25:208-212.
8. Sulica RL et al. (1994) Eccrine angiomatous hamartoma (nevus): Immunohistochemical findings and review of literature. J Cutan Pathol 21: 71-75
9. Theunuo RVR et al (2023) Linear eccrine angiomatous hamartoma. Indian J Dermatol Venereol Leprol 8:1-3.
10. Tsuji T, Sawada H (1999) Eccrine angiomatous hamartoma with verrucous features. Br J Dermatol 141: 167-169
11. Yamamoto T et al. (2017) Eccrine Angiomatous Hamartoma in a Patient with Nevus Depigmentosus and Nevus Spilus. Indian J Dermatol 62:99-100.