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The generalized bullous fixed drug exanthema (drug reaction) is a multilocular variant of the "localized" fixed drug reaction. Fixed Drug Reaction.
1. multilocular red plaques with the typical appearance of the "localized fixed drug reaction" see there.
2. formation of a large, blurred red plaque, with or without blistering, with or without extensive exfoliation of the epidermis. The clinical picture resembles a localized form of Stevens-Johnson syndrome.
Prof. Dr. med. Peter Altmeyer