DefinitionThis section has been translated automatically.
Antidepressant.
IndicationThis section has been translated automatically.
Depressive syndromes, regardless of their nosological classification; anxiety syndromes; mild withdrawal syndromes in cases of alcohol, drug or medicine addiction; restlessness, anxiety, sleep disorders and functional organ problems.
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Dosage and method of useThis section has been translated automatically.
Gradual dosage at the beginning and gradual discontinuation at the end of the treatment. Start with 10-25 mg, depending on the severity of the disease, gradual increase to max. 75-150 mg doxepin in outpatient therapy. In patients over 60 years of age about half of the recommended dose is usually sufficient. Up to 100 mg can be administered as a single dose in the evening 2-3 hours before bedtime.
Undesirable effectsThis section has been translated automatically.
Among others, exanthema, hyperhidrosis, hair loss, dry mouth, salivation, difficulty swallowing, gastrointestinal disorders, cardiac arrhythmia, gynecomastia, loss of libido, syndrome of inadequate ADH secretion.
InteractionsThis section has been translated automatically.
The antihypertensive effect of nitrates and antihypertensive drugs can be enhanced, the effect of reserpine can be weakened.
ContraindicationThis section has been translated automatically.
Allergy to doxepin, urinary retention, paralytic ileus, narrow-angle glaucoma, MAO inhibitors, delirium, childhood.
PreparationsThis section has been translated automatically.
Aponal, Sinquan
Prof. Dr. med. Peter Altmeyer