Degeneration, granular

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Acanthokeratolysis

Definition
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Histological term for premature tonofibril fusion and keratohyalin formation disorder in the upper prickle cell layer due to a defect of keratin 1 or 10. acantholysis of the epithelial cells is detectable in the erythrodermia congenitalis ichthyosiformis bullosa as well as in the epidermolytic epidermal nevus (see below naevus verrucosus).

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Last updated on: 29.10.2020