Synonym(s)
Biographical detailsThis section has been translated automatically.
Henri-Alexandre Danlos , a French physician and dermatologist, was born in Paris on March 26, 1844 and died in Chatoux on September 12, 1912. He spent his entire life in his native city of Paris. His father wanted his son to join the family business, and his initial training was geared towards this, but he himself opted for medicine and switched to a medical degree course without his parents' knowledge. Danlos graduated with honors in 1869 and submitted his doctoral thesis entitled "The relationship between menstruation and skin diseases" in 1874.
Danlos was initially primarily interested in laboratory work, but also retained his early interest in chemistry and conducted research in the laboratory of Charles-Adolphe Wurtz (1817-1884) in the early stages of his career. In 1881, at the age of 37, he passed the examination for consultant status - médecin des hôpitaux - and received extensive clinical training under Edmé Félix Alfred Vulpian (1826-1887).
In 1885, Danlos became chef de service at the Hôpital Tenon, where he spent five years, followed by five years in the civil service. This period was unhappy for Danlos, as he suffered from a protracted and painful illness and became withdrawn and pessimistic. In 1895, at the age of 51, Danlos obtained a position at the Hôpital Saint Louis in Paris. He worked in general medicine and gained a reputation as a caring physician and excellent diagnostician, but became increasingly involved in the development of new therapeutic techniques in dermatology.
Danlos carried out numerous careful studies on the use of various arsenic and mercury preparations in the treatment of syphilis and other skin diseases and was a pioneer in the use of radium for the treatment of lupus erythematosus of the skin. Together with Eugene Bloch, he was the first to bring radium into contact with a tuberculous skin lesion.
The name Danlos is known in the eponym Ehlers-Danlos syndrome.
LiteratureThis section has been translated automatically.
- Grotz W et al. (2024) Hypermobility and Ehlers-Danlos syndrome. Different diseases, uniform concept. CME 10: 19-29
- Obituary: Bulletin de la Societé française de dermatologie et de syphiligraphie, Paris, 1912: 500.
- Patel P et al. (2016) The Rise of Henri-Alexandre Danlos and His Contributions to Dermatologic Therapeutics and Radiation Research. JAMA Dermatol 152:1113.
