Cyproterone acetate
Definition This section has been translated automatically.
Half-life This section has been translated automatically.
48 ± 10 h
Indication This section has been translated automatically.
Medium to severe acne, seborrhea, alopecia androgenetica (see alopecia androgenetica in women, alopecia androgenetica in men), hirsutism in women.
Limited indication This section has been translated automatically.
6 weeks before planned operations, long-term immobilization (e.g. after accidents), smokers > 30 years, liver diseases (e.g. porphyria), renal failure, heart failure, Z.n. thrombophlebitis, Raynaud's disease, peripheral circulatory disorders, edema.
Dosage and method of use This section has been translated automatically.
Initially 100 mg/day p.o. from 1st to 10th day of cycle in combination with antiandrogen-estrogen combination preparation (e.g. Diane 35), after clinical improvement 50 mg/day from 1st to 10th day of cycle in combination with Diane 35 or Diane 35 alone.
Notice! In case of absence of menstruation exclude pregnancy before taking again!
Undesirable effects This section has been translated automatically.
Anemia, weight gain, gynecomastia, galactorrhea, menstrual disorders, libido loss, cholestasis, liver dysfunction, angioedema, thrombosis, fatigue, depression, muscle weakness, osteoporosis.
Interactions This section has been translated automatically.
The blood sugar-lowering effect of insulin, metformin and sulfonylureas is reduced.
Contraindication This section has been translated automatically.
Pregnancy, lactation, liver diseases, Z.n. pemphigoid gestationis, liver tumours, consuming diseases (except Prostata-Ca), tendency to thrombosis, sickle cell anaemia, severe diabetes mellitus, severe chronic depression, adolescents before the end of puberty.
Preparations This section has been translated automatically.
Androcur®, Virilit®