Cross syndrome E70.38

Author: Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 22.08.2024

Dieser Artikel auf Deutsch

Synonym(s)

Cross-McKusick-Breen Syndrome; Cross-McKusick-Breen Syndromes; Kramer syndrome; Kramer Syndrome; MIM 257800; Oculocerebral syndrome with hypopigmentation; Osyndromes with hypopigmentation

History
This section has been translated automatically.

Cross HE et al. 1967

Definition
This section has been translated automatically.

Rare, autosomal recessive inherited syndrome (genetic defect not yet clarified) with oculocutaneous hypopigmentation, microphthalmia, corneal opacity, nystagmus, weakness, spasticity (Cross HE et al. 1967). The disease is observed in the Amish.

Manifestation
This section has been translated automatically.

Skin and eye changes from birth, neurological disorders in the first weeks of life.

Therapy
This section has been translated automatically.

Primarily neurological and ophthalmological clinical picture.

Dermatological: light protection (e.g. Anthelios), eye protection, because of the sensitivity of the skin regular check for malignant transformations.

Literature
This section has been translated automatically.

  1. Cross HE et al (1967) A new oculocerebral syndrome with hypopigmentation. J. Pediat. 70: 398-406

  2. Scheinfeld NS (2003) Syndromic albinism: a review of genetics and phenotypes. Dermatol Online J 9:5.

Outgoing links (1)

Light protection;

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

Authors

Last updated on: 22.08.2024