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Cromoglicic acid

Authors:Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 18.12.2020

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Synonym(s)

Acidum cromoglicium; CAS No: 16110-51-3; Cromolyn; Disodium cromoglicic acid

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DefinitionThis section has been translated automatically.

Cromoglicic acid is an antiallergic, antihistamine, mast cell stabilizer.

Pharmacodynamics (Effect)This section has been translated automatically.

Inhibits the release of mediators (including histamine, PAF) by stabilizing the membranes of the mast cell by blocking chloride channels Cromoglicic acid has a half-life of 60 - 90 minutes. Therefore, the substance must be applied at least 4 times/day.

IndicationThis section has been translated automatically.

The active substance is used mainly in the prevention of bronchial asthma, allergic rhinitis and allergic conjunctivitis.

Dosage and method of useThis section has been translated automatically.

Adults: 4 times/day 2 capsules p.o., Children from 2 to 4 years: 4 times/day 1 capsule p.o.
Nasal spray: 4 times/day 1 spray in each nostril.
Dosage aerosol: 4-8 times/day 2 sprays per inhalationem
Eye drops: 4 times/day 1 trp. instill.

Undesirable effectsThis section has been translated automatically.

Since cromoglicic acid is almost completely broken down when taken, the active ingredient is only used locally or by inhalation. Side effects include local irritation such as coughing, hoarseness, and rarely bronchospasm or myalgia.

PreparationsThis section has been translated automatically.

AARANE® N 1 mg/0.5 mg per spray burst Compressed gas inhalation, suspension Sanofi-Aventis Deutschland GmbH

Allergo-COMOD® eye drops (without preservatives) Ursapharm Arzneimittel GmbH

Colimune® sachets 100 mg granules for oral solution Sanofi-Aventis Deutschland GmbH

Crom-Ophtal® eye drops Dr. Winzer Pharma GmbH

Authors

Last updated on: 18.12.2020

Authors: Prof. Dr. med. Peter Altmeyer Prof. Dr. med. Martina Bacharach-Buhles