Colistin

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Colistin sulphate

Definition
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Narrow spectrum antibiotic (polypeptide antibiotic).

Spectrum of action
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Bactericide against Gram-negative bacteria (P. aeruginosa, E. coli, H. influenzae, Salmonella, Shigella).

Indication
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Selective intestinal decontamination according to Stoutenbeck.

Dosage and method of use
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Adults: 4 times/day 4 tr., teenagers 4 times/day 3 tr., school children (7-12 years) 4 times/day 2 tr.

Undesirable effects
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Rare allergic reactions, gastrointestinal disorders (nausea, vomiting, stomach pain, diarrhea).

Contraindication
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Premature and newborns, hypersensitivity to polymyxins, patient with damaged intestinal mucosa (Crohn's disease, ulcerative colitis)

Preparations
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Colistin

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Last updated on: 29.10.2020