Clear cell hidradenomaD23.L

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Bright cell myoepithelioma; clear cell hidradenoma; Clear cell myoepithelioma

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DefinitionThis section has been translated automatically.

Benign adnexal tumor with apocrine (and eccrine?) differentiation. S.u. Hidradenoma.

EtiopathogenesisThis section has been translated automatically.

Clear (or light) cell variant of the nodular hidradenome

ManifestationThis section has been translated automatically.

Occurring in adulthood.

LocalizationThis section has been translated automatically.

Face, head hair, skin, chest area.

Clinical featuresThis section has been translated automatically.

Predominantly solitary tumour, up to 3 cm in size, fused with the epidermis, easily displaceable towards the subcutis, partly solid, partly cystic. Central ulceration is possible.

HistologyThis section has been translated automatically.

Lobularly arranged epithelioid cells in the corium. Cavities, plant cell-like, hydrophobic-clear cells with sharply defined cytoplasmic membrane.

Differential diagnosisThis section has been translated automatically.

TherapyThis section has been translated automatically.

Excision with small safety distance (5 mm) is curative.

Progression/forecastThis section has been translated automatically.

Rarely is the occurrence of malignant degeneration with locally destructive growth possible.

LiteratureThis section has been translated automatically.

  1. Ambrojo P et al (1989) Clear-cell syringoma. Dermatologica 178: 164-166
  2. Faulhaber D et al (2000) Clear cell hidradenoma in a young girl. J Am Acad Dermatol 42: 693-695
  3. Harada T (2003) Malignant clear-cell hidradenoma associated with pseudoepitheliomatous hyperplasia on the forehead. Ann Plast Surgery 50: 443-444
  4. Sagi A et al (2002) Cystic clear cell hidradenoma of the thumb: case report of a rare hand tumor. Ann Plast Surgery 48: 337-338
  5. Will R et al (2000) Recurrent clear cell hidradenoma of the foot. Dermatol Surgery 26: 685-686

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Last updated on: 29.10.2020