Clarithromycin

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Acid-resistant macrolide antibiotic.

Half-life
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4–5 h

Spectrum of action
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Bordetella spp., Borrelia burgdorferi, Campylobacter jejuni, Chlamydia, Coxiella burneti, Haemophilus ducreyi, Helicobacter pylori, Legionella pneumophilia, Listeria monocytogenes, Moraxella catarrhalis, Mycobacterium avium intracellular complex, Mycoplasma pneumoniae, Neisseria gonorrhoeae, Rickettsia spp, Staphylococcus spp., Streptococcus spp.

Indication
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Pneumonia, skin infections.

Limited indication
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Liver dysfunction.

Dosage and method of use
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  • 2 times 250-500 mg/day p.o. before meals.
  • Children < 12 years: 15 mg/kg bw in the form of a suspension.

Undesirable effects
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S.u. Erythromycin. Less severe gastrointestinal side effects than erythromycin. Occasional thrombocytopenic purpura.

Contraindication
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Hypersensitivity, first trimester pregnancy.

Preparations
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Biaxin, Cyllind, Klacid, Mavid

Outgoing links (2)

Erythromycin; Macrolide antibiotics;

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Last updated on: 29.10.2020