Chromogranine a

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 27.02.2022

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Definition
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Chromogranin A labels secretory granules of neuroendocrine cells. Chromogranin A is expressed in Merkel cell carcinoma, neuroblastoma, small cell lung carcinoma (metastases), carcinoid. Together with synaptophysin, chromogranin A forms the most important marker for neuroendocrine tumors.

Literature
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  1. Hantschke M et al (2016) Immunohistological techniques. In: L. Cerroni et al. histopathology of the skin. Springer Publishing House Berlin-Heidelberg p. 29.

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Last updated on: 27.02.2022