Chromhidrosis, apocrine L75.1

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

apocrine chromium hydrosis; Chromhidrosis intrinsic; Chromhidrosis localized; Chromhidrosis real; intrinsic chromohidrosis; localized chromhidrosis; true chromic acid rose

Definition
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Secretion of coloured (yellow, black, blue, green) sweat from apocrine sweat glands due to increased deposition of lipofuscin. The different colours correspond to different oxidation levels of the pigment. A distinction is made between the axillary and facial form.

Manifestation
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Rarely found in whites; frequently found in members of the black ethnicity (10% of all blacks). Beginning after puberty, most pronounced at sexual maturity.

Localization
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Axilla; rarely localized on forehead and cheeks (aberrating apocrine sweat glands).

Clinical features
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Punctual discharge of coloured, most frequently yellow sweat, especially during emotional excitement. Discoloration of the underwear, possibly also of the axillary skin.

Diagnosis
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Sweat provocation test with adrenaline (selectively provokes apocrine glands), Minorsch sweat test.

Differential diagnosis
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Therapy
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No causal therapy known.

External therapy
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  • Although excision of the glandular tissue in the armpits is effective, in our opinion the surgical procedure is disproportionate to the disease.
  • Try capsaicin 0.01%, e.g. R037. Initially 2 times/day then increase in 0.05% steps every 3-4 days, depending on tolerance and therapy success.

Literature
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  1. Cilliers J et al (1999) The case of the red lingerie - chromhidrosis revisited. Dermatology 199: 149-152
  2. Marks JG (1989) treatment of apocrine chromhidrosis with topical capsaicin. J Am Acad Dermatol 21: 18-20
  3. Schwarz T et al. (1989) Apocrine Chromhidrosis. Dermatologist 40: 106-109
  4. Thami GP et al (2000) Red facial pseudochromhidrosis. Br J Dermatol 142: 1219-1220

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020