DefinitionThis section has been translated automatically.
Older cephalosporin.
Half-lifeThis section has been translated automatically.
1,4–2 h
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Spectrum of actionThis section has been translated automatically.
Citrobacter diversus, Corynebacterium diphtheriae, Erysopelothrix rhusiopathiae, E. coli, Klebsiella spp., Moraxella catarrhalis, Neisseria spp., Proteus mirabilis, Salmonella spp.
IndicationThis section has been translated automatically.
Respiratory, urinary tract, skin, soft tissue and wound infections caused by gram-positive pathogens (except listeria), gonorrhoea.
Dosage and method of useThis section has been translated automatically.
- Adults/children > 1 year: 2-3 g/day in 2-3 ED i.v.
- Children after the 1st month of life: 25-50 mg/kg bw/day.
- children after the 1st year of life: 50-100 mg/kg bw/day.
PreparationsThis section has been translated automatically.
Cefazolin, Elzogram
Note(s)This section has been translated automatically.
Cephalosporin is the most effective against staphylococci.
LiteratureThis section has been translated automatically.
- Stryjewski ME et al (2007) Use of vancomycin or first-generation cephalosporins for the treatment of hemodialysis-dependent patients with methicillin-susceptible Staphylococcus aureus bacteremia. Clin Infect Dis 44: 190-196
Prof. Dr. med. Peter Altmeyer