Cd95

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Apo-1; Fas

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DefinitionThis section has been translated automatically.

Cells: CD4+, CD8+ T cells, B cells, variable also on monocytes and granulocytes, tissue

Structure: Transmembrane glycoprotein (40-50 kDa)

Note: CD95 (also known as APO-1 or Fas) belongs to the tumor necrosis factors and is mainly responsible for apoptosis (programmed cell death). The ligand of Fas is FasL(CD178). CD95 is upregulated when cells are activated.

Application: FACS, IHC (P) (G)

(see below) Cluster of differentiation

LiteratureThis section has been translated automatically.

  1. Hantschke M et al (2016) Immunohistological techniques. In: L. Cerroni et al. histopathology of the skin. Springer publishing house Berlin-Heidelberg p. 26-33.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer