Synonym(s)
B29; B-cell antigen receptor complex-associated protein alpha chain; CD79b; Iga; Ig-alpha; Igb; MB-1; MB-1 membrane glycoprotein; Membrane-bound immunoglobulin-associated protein; Surface IgM-associated protein
DefinitionThis section has been translated automatically.
Pan B-lymphocyte marker (often more sensitive than CD20); B-cell lymphomas and leukemias.
CD79a, is a B cell receptor surface protein involved in the humoral immune response. CD79a is a cell type marker of B cells as well as their progenitor cells and is produced by B cells. It binds to CD79b. CD79a is necessary for cell differentiation of pro-B cells and pre-B cells.
CD79a is often used in combination with CD20 as a B cell marker for B cell lymphomas. Certain gene defects of CD79a are associated with a form of agammaglobulinemia.
LiteratureThis section has been translated automatically.
- Hantschke M et al (2016) Immunohistological techniques. In: L. Cerroni et al. histopathology of the skin. Springer Publishing House Berlin-Heidelberg p. 28.
Prof. Dr. med. Peter Altmeyer