DefinitionThis section has been translated automatically.
markers for: T cells, NK cells, monocytes, pre-B cells
Structure: Transmembrane protein (40 kDa)
Note: CD7 (gp40), belonging to the immunoglobulin superfamily, is also expressed in acute lymphocytic leukemia (T-cell ALL). Very early T-cell antigen. The marker combination CD3+CD4+CD7- is pathognomic for Sézary cells in peripheral blood.
Application: FACS, IHC (G), IF
LiteratureThis section has been translated automatically.
- Hantschke M et al (2016) Immunohistological techniques. In: L. Cerroni et al. histopathology of the skin. Springer publishing house Berlin-Heidelberg p. 26-33.
Prof. Dr. med. Peter Altmeyer