Cd63

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Cells: Granulocytes, monocytes, thrombocytes, melanoma cells

Structure: Glycoprotein (40-60 kDa)

Note: CD63 is an intracellular lysosomal granulaprotein which is translocated to the cell surface after activation of granulocytes/endothelial cells (activation marker). CD63 is identical to ME491, an antigen expressed by melanoma cells and associated with early stages of tumor progression.

Application: FACS, IHC (P

(see below) Cluster of differentiation

Literature
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  1. Hantschke M et al (2016) Immunohistological techniques. In: L. Cerroni et al. histopathology of the skin. Springer publishing house Berlin-Heidelberg p. 26-33.

Incoming links (1)

Basophil activation test;

Outgoing links (1)

CD classification;

Authors

Last updated on: 29.10.2020