Cd4

Author:Prof. Dr. med. Peter Altmeyer

All authors of this article

Last updated on: 29.10.2020

Dieser Artikel auf Deutsch

Synonym(s)

L3T4

Requires free registration (medical professionals only)

Please login to access all articles, images, and functions.

Our content is available exclusively to medical professionals. If you have already registered, please login. If you haven't, you can register for free (medical professionals only).


Requires free registration (medical professionals only)

Please complete your registration to access all articles and images.

To gain access, you must complete your registration. You either haven't confirmed your e-mail address or we still need proof that you are a member of the medical profession.

Finish your registration now

DefinitionThis section has been translated automatically.

markers for: T-helper cells, thymocytes, monocytes, macrophages, cortical thymocytes (sub), Langerhans cells

Structure: Transmembrane protein (59 kDa)

Application: FACS, IHC (P) (G), IF

(see below) Cluster of differentiation

General informationThis section has been translated automatically.

The CD4 molecule binds to MHC class II molecules and is a co-receptor for MHC class II antigen-induced activation. On thymocytes often co-expressed with CD8. CD4+ lymphocytes are involved in the synthesis of immunoglobulins by B cells. CD4 is a receptor for gp120 (envelope protein of HIV-1).

LiteratureThis section has been translated automatically.

  1. Hantschke M et al (2016) Immunohistological techniques. In: L. Cerroni et al. histopathology of the skin. Springer publishing house Berlin-Heidelberg p. 26-33.

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer