Cd11b

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

CR3A; integrin alpha M; integrin subunit alpha M; ITGAM; MAC-1; MAC1A; MO1A; Protein ITGAM PDB 1bho.png; SLEB6

Definition
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CD11b, also known as integrin alpha M or ITGAM, is a cytokine that belongs to the subfamily of beta2 (or leukocyte integrins). The coding gene is located on chromosome 16: 31.26 - 31.33 in humans.

CD11b is expressed on the surface of leukocytes involved in innate immunity functions. CD11b is mainly expressed by monocytes, granulocytes, macrophages and NK cells.

(see below) Cluster of differentiation

Outgoing links (2)

CD classification; Cytokines;

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Last updated on: 29.10.2020