Cd118

The term Cluster of Differentiation, abbreviation "CD", refers to groups of cellular surface features that have been ordered according to biochemical or functional criteria. The CD classification enables a comprehensible transparency in immunohistological and immunological diagnostics.

CD118, also known as "Leukemia Inhibitory Factor Receptor" or LIFR, is a transmembrane glycoprotein encoded by the LIFR receptor. CD118 is associated with CD130, both proteins forming the effective LIF receptor complex. The CD118/CD130 complex is widely expressed by numerous cells, including hematopoietic stem cells, hepatocytes, adipocytes, myoblasts, neural and glial cells.

(see below) Cluster of differentiation