Synonym(s)
Carapace Cancer; Carcinoma en cuirasse
DefinitionThis section has been translated automatically.
Form of skin metastasis with plate-like, often dark red induration of the skin by intracutaneous (tissue clefts) and lymphogenic dissemination of tumor cells with consecutive fibrosis and edema formation. Especially in the case of breast carcinoma, partial walling of the entire thorax = maximum variant of an erysipelas carcinomatosum.
Differential diagnosisThis section has been translated automatically.
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TherapyThis section has been translated automatically.
The aim of treatment is to maintain the best possible quality of life despite an unfavorable prognosis. Radiotherapy or cytostasis possible. Treatment regimen depends on the spread of the metastases and the primary tumor.
The combination of radiotherapy and local hyperthermia in cases of resistance to therapy shows better results. There are indications that the additional use of immune checkpoint inhibitors could be beneficial.
Progression/forecastThis section has been translated automatically.
Serious
LiteratureThis section has been translated automatically.
- Sindermann H et al. (1995) Miltefosine Solution: Prognostic factors for the outcome of topical treatment of skin metastatic breast cancer. Oncology 17: 21-26
- Oldenborg S et al (2018) Reirradiation+ hyperthermia for recurrent breast cancer en cuirasse. Radiation Oncol;194: 206-214
- Sengedorj A et al. (2022) The Effect of Hyperthermia and Radiotherapy Sequence on Cancer Cell Death and the Immune Phenotype of Breast Cancer Cells. Cancers (Basel). 19;14:2050.
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Incoming links (4)
Carapace cancer; Carcinoma en cuirasse; Erysipelas carcinomatosum; Skin metastases;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer