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Calcinosis cutis (overview)L94.2

Author:Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

calcification of the skin; Calcinosis of the skin; cutaneous calcification; Cutaneous calcinosis

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DefinitionThis section has been translated automatically.

Deposition of precipitated calcium salts (amorphous calcium phosphate with small amounts of calcium carbonate) in the dermis and subcutis.

ClassificationThis section has been translated automatically.

A distinction is made between:

Remark: In the American literature the terms calcinosis metabolica, dystrophica and idiopathica are used synonymously. This seems to be a useful and pragmatic solution from a clinical point of view. Therefore, in this encyclopedia, these terms are listed individually, but are treated under the term "Calcinosis dystrophica".

EtiopathogenesisThis section has been translated automatically.

Calcium and phosphate ions are present in stable solution in the extracellular fluid. If the solubility point is exceeded, precipitation of hydroxyapatite occurs. Cause: Systemic (metastatic calcinosis) or local, by dystrophic local processes, e.g. alkalization, calcinosis metabolica. In metastatic calcinosis the serum calcium phosphate levels are pathological, in the dystrophic and metabolic form normal.

ManifestationThis section has been translated automatically.

More common in systemic scleroderma, for example, see CREST syndrome.

Differential diagnosisThis section has been translated automatically.

Oxalosis of the skin

TherapyThis section has been translated automatically.

calcinosis metabolica, calcinosis metastatica, calcinosis dystrophica, calcinosis idiopathica

LiteratureThis section has been translated automatically.

  1. Cambiaghi S (2000) Fingertip calcinosis cutis. Cutis 66: 465-467
  2. Deza G et al (2016) Solitary Plaque-type Morphea with Dystrophic Calcinosis Cutis. Acta Derm Venereol 96:418-419
  3. Lai CH et al (2003) Congenital calcinosis cutis of the ear. J Am Acad Dermatol 49: 122-124
  4. Larralde M et al (2003) Calcinosis cutis following liver transplantation in a pediatric patient. Pediatric Dermatol 20: 225-228
  5. Marzano AV et al (1999) Dystrophic calcinosis cutis in subacute lupus. Dermatology 198: 90-92
  6. Niederauer HH et al (1992) Calcinosis cutis in Coxsackie virus infection. Z Skinkr 67: 1101-1104
  7. Ogretmen Z et al (2002) Calcinosis cutis universalis. J Eur Acad Dermatol Venereol 16: 621-624
  8. Poormoghim H et al (2016) Systemic sclerosis and calcinosis cutis: response to rituximab. J Clin Pharm Ther 41: 94-96
  9. Salmhofer W et al (1995) Cutaneous calciphylaxis in chronic renal failure. Dermatologist 46: 726-731
  10. Zouboulis CC et al (1990) Calcinosis cutis: Cutaneous manifestations of generalized calcinosis in renal hyperparathyroidism. dermatologist 41: 212-217

Authors

Last updated on: 29.10.2020

Author: Prof. Dr. med. Peter Altmeyer